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Fig. 6 | Malaria Journal

Fig. 6

From: Comparison of ELISA with electro-chemiluminescence technology for the qualitative and quantitative assessment of serological responses to vaccination

Fig. 6

a Correlation plots of the ELISA and ECLIA titres for CSP-FL (left), CSP-repeat (NANP; center), and C-term (right) antigens from samples from 30 NHP animals immunized with a particle-based CSP vaccine. Slope and correlation coefficient are shown. b Bland–Altman plots comparing ELISA and ECLIA assays for the aforementioned antigens. The mean difference between the ELISA and ECLIA titres (black line) and the 95% confidence interval of the difference (dotted black line) are shown. The systematic trend in the difference in ELISA and ECLIA titres as a function of antibody concentration is represented by the slope (dashed red line), along with the 95% confidence interval of the slope (solid red line). The slope is labelled along with a corresponding p-value (*p < 0.01, **p < 0.001)

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Malaria Journal

ISSN: 1475-2875

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