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Table 5 Effect of plasma Sulfadoxine concentration on maternal malaria and adverse birth outcomes

From: Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania

Variables

Geometric mean, SDX conc. (± SD) μg/mL

p-value

Peripheral malaria

 Positive

6.0 ± 1.28

 

 Negative

10.84 ± 2.52

0.37

Placental malaria

 Positive

20.02 ± 2.75

0.24

 Negative

10.62 ± 2.51

 

Maternal Hb, g/dL

 < 11.0

10.19 ± 2.49

0.49

 ≥ 11.0

11.31 ± 2.54

 

Fetal Hb, g/dL

 < 12.5

10.76 ± 2.14

1.00

 ≥ 12.5

10.76 ± 2.55

 

Birth weight (Kg)

 < 2.5

9.90 ± 2.54

0.74

 ≥ 2.5

10.84 ± 2.52

 

Fetal maturity at delivery

 Premature

8.79 ± 2.77

0.29

 Mature

11.10 ± 2.47

 
  1. IPTp-SP intermittent preventive malaria in pregnant women using SDX-pyrimethamine, SDX SDX, Hb haemoglobin, LBW low birth weight, NBW normal birth weight, SD standard deviation