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Table 2 Clinical characteristics of CLI validation cohort

From: Depleted circulatory complement-lysis inhibitor (CLI) in childhood cerebral malaria returns to normal with convalescence

Validation cohortClinical groups [Total N = 177 at onset; N = 61 at recovery]
UMCMSMADCCC
Onset
N (%)
38 (16.3%)35 (24.5%)30 (16.3%)39 (11%)35 (27.3%)
Recovery
N (%)
18 (36%)25 (32%)18 (32%)N/AN/A
Age (months)
Median (IQR)
45 (6–145)49 (15–165)37 (6–150)55 (5–150)50 (10–100)
Sex: F/M24/1420/1514/1619/2020/15
PCV (%)
At onset
Median (IQR)
32 (27–35)25 (23–30)13 (11–15)14 (8–23)34 (32–35)
PCV (%)
At recovery
Median (IQR)
35 (29–40)34 (27–40)34 (27–37)35 (28–)35 (27–40)
Parasite density
At onseta
Median (IQR)
27,429
(1901–54,680)
5590
(1314–81,923)
32,131
(2487–103,822)
N/AN/A
  1. aParasite density not significantly different between malaria groups
  2. N number, IQR interquartile range, PCV pack cell volume, UM uncomplicated malaria, SMA severe malarial anaemia, CM cerebral malaria