Table 1 Molar amount of NH₄SCN needed to release 50% of bound antibody

% Ab positive

100 (40/40)

90 (36/40)

100 (40/40)

98 (39/40)

68 (27/40)

Median MFI

(95% CI)^a

(1:1000 dilution)

16,799

(13,176, 18,855

13,815

(11,189, 17,637)

9054

(6907, 14,221)

9177

(5309, 11,151)

2066

(1287, 3477)

Molars of chaotrope to release 50% Ab bound (mean ± SD)

2.31 M ± 0.44

2.25 ± 0.33

2.32 ± 0.82

1.71 ± 0.22

1.70 ± 1.72

n = 57 1-year old infants

AMA1

EBA-175

MSP1-42

MSP2

MSP3

% Ab positive

72 (41/57)

49 (28/57)

9353/57

88 (50/57)

37 (21/57)

Median MFI

(95% CI)^a

(1:100 dilution)

9664

(5717, 13,906)

1094

(673, 1584)

8974

(4365, 11,808)

5536

(2335, 9276)

1247

(750, 1653)

Molars of chaotrope to release 50% Ab bound Ab

1.78 M ± 0.27

2.0 ± 0.50

2.1 ± 0.59

1.6 ± 1.1

1.6 ± 0.12