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Fig. 1 | Malaria Journal

Fig. 1

From: Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2/3 copy number variation in Plasmodium falciparum

Fig. 1

Distribution of fold-changes of samples from whole-blood (a) or dried blood spots (b) as measured by the plasmepsin 2pfmdr1 TaqMan qPCR assay. Tick marks underneath the bar graphs indicate individual sample status for the breakpoint PCR assay (BP, top line), with blue indicating no breakpoint detected and red containing the breakpoint, or exo-E415G SNP (EXO, bottom line), where yellow represents the wildtype E amino acid and green is the mutant G amino acid. Bars are coloured by their predicted plasmepsin 2 copy number of either 1, 2, 3, or 4+ (green, yellow, orange, and red, respectively)

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