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Fig. 7 | Malaria Journal

Fig. 7

From: The thermostability of the RTS,S/AS01 malaria vaccine can be increased by co-lyophilizing RTS,S and AS01

Fig. 7

Evolution of QS-21 content and QS-21 hydrolysis upon storage. Liquid AS01 and CL-vac were stored at 4, 30, 37 or 45  °C for up to 12 months and the QS-21 content and the level of QS-21 hydrolysis were measured at different time points. A short heat expedition was made for CL-vac consisting of 1 month at 45  °C after storage for 12 months at 30  °C and the two parameters were also measured at this final time point. The dashed lines indicate the respective acceptance criteria set for the release of liquid AS01 (lower limit for QS-21 content and upper limit for QS-21H). Black bar represents 200 µm

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