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Fig. 9 | Malaria Journal

Fig. 9

From: The thermostability of the RTS,S/AS01 malaria vaccine can be increased by co-lyophilizing RTS,S and AS01

Fig. 9

Electronic microscopy analysis of CL-vac after storage. Images obtained by TEM with negative staining of CL-vac after storage for 6 months at 37  °C (a), 6 months at 45  °C (b) or 1 year at 30  °C (c) before reconstitution, and liquid AS01 after storage for 6 months at 37  °C (d) are shown. White arrow, perforation of the liposome membrane. Thin black arrow, RTS,S particles. Thick black arrow, small liposome. Black dashed arrow, ghosts of liposome membrane. White dashed arrow, Iscom’s-like structures. Black dot-arrow, tubular structures

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Malaria Journal

ISSN: 1475-2875

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