From: M1 macrophage features in severe Plasmodium falciparum malaria patients with pulmonary oedema
Parameters | Severe malaria patients (mean ± SEM) | p-values | |
---|---|---|---|
Non-PE (n = 12) | PE (n = 12) | ||
Age (years) | 24.00 ± 5.09 | 27.00 ± 2.53 | 0.600 |
Haematocrit (%) | 32.20 ± 2.91 | 24.00 ± 1.53 | 0.032* |
Blood urea nitrogen (BUN) (mg/dl) | 21.30 ± 3.16 | 51.07 ± 13.07 | 0.072 |
Creatinine (mg/dl) | 1.45 ± 0.29 | 3.28 ± 0.72 | 0.023* |
Alanine transaminase (ALT) (U/l) | 179.33 ± 150.42 | 142.75 ± 10.76 | 0.355 |
Aspartate aminotransferase (AST) (U/l) | 269.75 ± 193.05 | 133.25 ± 13.39 | 0.257 |
Alkaline phosphatase (ALP) (U/l) | 75.33 ± 36.75 | 55.15 ± 0.57 | 0.133 |
Albumin (g/l) | 2.93 ± 0.36 | 2.50 ± 0.26 | 0.375 |
Globulin (g/dl) | 2.75 ± 0.19 | 3.15 ± 0.38 | 0.384 |
Total bilirubin (mg/dl) | 3.33 ± 1.75 | 6.87 ± 3.82 | 0.467 |
Direct bilirubin (mg/dl) | 8.09 ± 4.13 | 12.08 ± 6.21 | 0.630 |
White blood cell (WBC) (/µl) | 25,291 ± 15,400 | 25,200 ± 12,947 | 0.101 |
Parasitaemia/µl on admission | 401.00 ± 369.95 | 93.50 ± 56.28 | 0.485 |
Days of fever | 3.25 ± 0.52 | 4.33 ± 0.92 | 0.418 |