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Table 1 Evaluation of best binding affinity of L-lactate dehydrogenase and haem with the studied ligands

From: In silico and in vivo anti-malarial investigation on 1-(heteroaryl)-2-((5-nitroheteroaryl)methylene) hydrazine derivatives

Complexes Best binding affinity to PfLDH(Kcal/mol) Complexes Best binding affinity to Haem (Kcal/mol)
PfLDH-lig1 − 8.2 Heme-lig1 − 5.4
PfLDH -lig2 − 8.0 Heme-lig2 − 5.1
PfLDH -lig3 − 8.4 Heme-lig3 − 5.5
PfLDH -lig4 − 8.2 Heme-lig4 − 5.2