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Table 2 Prevalence of SNPs in pfk13, pfcoronin, pfcrt, and pfmdr1 in Pakistan, 2018–2019

From: Surveillance of genetic markers associated with Plasmodium falciparum resistance to artemisinin-based combination therapy in Pakistan, 2018–2019

Gene

N

Wild Typea N (%)

Mutantb N (%)

Mixedc N (%)

Pfk13

121

121 (100)

0 (0)

0 (0)

Pfcoronin

149

149 (100)

0 (0)

0 (0)

Pfmdr1 N86Y

179

137 (76.5)

29 (16.2)

13 (7.3)

Pfmdr1 Y184F

172

143 (83.1)

18 (10.5)

11 (6.4)

Pfmdr1 D1246Y

173

173 (100)

0 (0)

0 (0)

Pfcrt K76T

179

3 (1.7)

164 (91.2)

12 (6.7)

  1. a Wild type alleles include Pfmdr1 N86, Y184, D1246, and Pfcrt K76
  2. b Mutant alleles include Pfmdr1 86Y, 184F, 1246Y, and Pfcrt 76T
  3. c Mixed alleles include Pfmdr1 N86Y, Y184F, D1246Y and Pfcrt K76T mixed infections