Table 2 Molecular descriptors of anti-malarial drugs
From: In silico analysis for factors affecting anti-malarial penetration into red blood cells
Drug | Rot | HBA | HBD | Ali carbo | Ali het | Aro carbo | Aro het | Sat carbo |
|---|---|---|---|---|---|---|---|---|
Amodiaquine | 6 | 4 | 2 | 0 | 0 | 2 | 1 | 0 |
Arteether | 2 | 5 | 0 | 1 | 4 | 0 | 0 | 1 |
Artemether | 1 | 5 | 0 | 1 | 4 | 0 | 0 | 1 |
Artemisinin | 0 | 5 | 0 | 1 | 4 | 0 | 0 | 1 |
Artesunate | 4 | 7 | 1 | 1 | 4 | 0 | 0 | 1 |
Chloroquine | 8 | 3 | 1 | 0 | 0 | 1 | 1 | 0 |
Dihydroartemisinin | 0 | 5 | 1 | 1 | 4 | 0 | 0 | 1 |
Doxycycline | 2 | 9 | 7 | 3 | 0 | 1 | 0 | 1 |
Mefloquine | 2 | 3 | 2 | 0 | 1 | 1 | 1 | 0 |
Piperaquine | 6 | 6 | 0 | 0 | 2 | 2 | 2 | 0 |
Primaquine | 6 | 4 | 2 | 0 | 0 | 1 | 1 | 0 |
Proguanil | 2 | 2 | 5 | 0 | 0 | 1 | 0 | 0 |
Pyrimethamine | 2 | 3 | 3 | 0 | 0 | 1 | 1 | 0 |
Quinine | 4 | 4 | 1 | 0 | 3 | 1 | 1 | 0 |
Sulfadoxine | 5 | 7 | 2 | 0 | 0 | 1 | 1 | 0 |