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Table 1 Baseline demographic and clinical characteristics of patients in control vs intervention arm

From: Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial

Parameters

Control armb

(N = 141)

Intervention armb

(N = 139)

Sex, n (%) female

65 (46.0)

59 (42.5)

Age (years), median (IQR)

10 (5–17)

10 (5–14)

Age groups

 < 5 years, n (%)

48 (34.0)

35 (25.2)

 5–14 years, n (%)

49 (34.8)

71 (51.1)

 ≥ 15 years, n (%)

44 (31.2)

33 (23.7)

Weight (kg), median (IQR)

26 (16.5–49.5)

27 (18–43)

Screening P. falciparum parasitaemia (p/µL), geometric mean (95% CI)

13,355 (9762–18,272)

16,986 (12,936–22,305)

Enrollment P. falciparum parasitaemia (p/µL), geometric mean (95% CI)a

15,744 (10,949–2263)

16,561 (11,812–23,219)

Patients with P. falciparum gametocytaemia, n (%)

3 (2.1)

1 (0.7)

Haemoglobin (g/dL), median (IQR)

12.2 (10.6–13.3)

12.0 (10.7–13.1)

Fever (axillary temperature ≥ 37.5 °C), n (%)

109 (77.3)

110 (79.1)

Axillary temperature (°C), median (IQR)

38.4 (37.6–39.0)

38.2 (37.7–39.1)

  1. IQR inter-quartile range
  2. aEnrollment parasitaemia was determined about 1–2 h from completion of screening just before the first dose
  3. bControl arm received standard treatment with artemether–lumefantrine for 3 days and intervention arm received extended treatment with artemether–lumefantrine for 6 days with single low-dose primaquine