Skip to main content

Table 2 Treatment outcomes by treatment arm as defined by the WHO at day 28 and 42

From: Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial

Endpoint (treatment outcome)

Control arm

Intervention arm

Early treatment failure, n (%)

0

0

Late clinical failure before D7, n (%)

0

0

Late clinical failure, on or after D7 n/N (%)

14/121 (11.6)

6/121 (5.0)

 Due to recrudescence

1

0

 Due to reinfection

11

3

 Undetermined or missing PCR data n/N

2

3

Late parasitological failure, n/N (%)

7/121 (5.8)

8/121 (6.6)

 Due to recrudescence

2

2

 Due to reinfection

2

5

 Undetermined or missing PCR data

3

1

Adequate clinical and parasitological response by D28, n/N (%)

115/121 (95.0)

118/121 (97.5)

Adequate clinical and parasitological response by D42, n/N (%)

100/103 (97.1)

107/109 (98.2)

No treatment outcome

 Lost to follow-up total, n/N (%)

17/141 (12.1)

17/139 (12.2)

 Withdrew consent or protocol violation n/N (%)

3/141 (1.4)

1/139 (0.7)