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Table 4 Proportion of PCR positive patients and respective parasite densities at days 3–42 by treatment arms

From: Parasite clearance, cure rate, post-treatment prophylaxis and safety of standard 3-day versus an extended 6-day treatment of artemether–lumefantrine and a single low-dose primaquine for uncomplicated Plasmodium falciparum malaria in Bagamoyo district, Tanzania: a randomized controlled trial

Day of assessmentPCR positivityp
Control arm n/N (%)Intervention arm n/N (%)
D3104/131 (79.4%)113/134 (84.3%)0.34
D5b80/130a (61.5%)89/134 (66.4%)0.44
D7b71/129a(55.0%)70/134 (52.2%)0.71
D2826/121 (21.5%)24/122 (19.7%)0.75
D28c15/102 (14.7%)16/111 (14.4%)1.00
D4220/105 (19.1%)25/116 (21.6%)0.74
D42c15/99 (15.2%)18/108 (16.7%)0.85
Day of assessmentParasite density determined by qPCR (p/µL)p
Geometric mean; rangeGeometric mean; range
D32; < 1–892; < 1–10510.98
D5b1; < 1–901; < 1–2080.07
D7b< 1; < 1–15< 1; < 1–1150.29
D2821; < 1–98,1952; < 1–35260.03
D28c2; < 1–32582; < 1–35260.10
D4217; < 1–101,748124; < 1–64,8130.13
D42c4; < 1–139525; < 1–60,0940.15
  1. aThere was one filter paper missing on D5 and two filter papers missing on day 7 in the control arm
  2. bPrimary outcome variable
  3. cAnalysis was repeated after removing microscopy determined recurrent parasitemia patients