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Table 5 Mean QTc change between treatment arms

From: Electrocardiographic safety evaluation of extended artemether-lumefantrine treatment in patients with uncomplicated Plasmodium falciparum malaria in Bagamoyo District, Tanzania

 

Intervention arm (n = 103)

Control arm (n = 92)

Mean difference

95% CI

P value*

All patients (n = 195)

ΔQTcBψ

1.9 (30.1)

− 9.4 (30.9)

11.4

2.7–20.0

0.010

− 3.4 (30.9)

ΔQTcFψ

16.2 (28.2)

2.7 (29.1)

13.4

5.3–21.5

0.001

9.8 (29.3)

ΔQTcB¥

3.1 (22.1)

− 6.4 (25.6)

9.5

2.7–16.2

0.006

− 1.4 (24.2)

  1. Data are means (standard deviation). Values are reported in milliseconds
  2. Italic values indicate significance of p value (p < 0.05)
  3. * P values were calculated using the independent t-test for difference in mean change in QTc interval between the treatment arms
  4. ψManually measured data
  5. ¥Automatically obtained data from machine
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Malaria Journal

ISSN: 1475-2875

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