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Table 2 CYP3A4 wild-type individuals for lumefantrine metabolism and parasite pfmdr1 mutation(s) among those with delayed parasite clearance (day 3 positive)

From: Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana

Sample number

CYP3A4 genotype

pfmdr1 mutation (s)

1

AA

F184

2

AA

F184

3

AA

F184

4

AA

F184

5

AA

F184

6

AA

F184

7

AA

F184

8

AA

Y86, F184

9

AA

F184

10

AA

F184

11

AA

F184

12

AA

F184

13

AA

F184

14

AA

F184

15

AA

F184

16

AA

F184

  1. Sixteen of the samples with delayed clearance had the CYP3A4 wild-type individuals for lumefantrine metabolism and parasite pfmdr1 mutation(s) as indicated
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Malaria Journal

ISSN: 1475-2875

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