Fig. 7
Mean parasitaemia of filtered Plasmodium vivax Aotus-derived iRBCs ex vivo cultures co-cultivated with Aotus or human malaria-naïve RBCs. Cultures were maintained with McCoy’s5A medium supplemented with 25% human serum or co-cultivated with Aotus (A) or human (H) malaria-naïve RBCs. Mean ± SEM of four technical replicates. p = Statistical significance Mann–Whitney U non-parametric one-tail t-test. Donor Aotus MN29038: parasitaemia density = 142.1 × 103 × μL; stage differential proportions = rings 83%, trophozoites 27%, schizonts 0%; post-inoculation day 15