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Table 4 Factors associated with pfhrp2/3 deletions (overall)

From: Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

Variable

Univariable

Multivariable

OR (95% CI)

p-value

aOR (95% CI)

p-value

Gender

 Male

1.00

 

1.00

 

 Female

1.20 (0.55–2.60)

0.646

1.24 (0.55–2.80)

0.598

Age (years)

 < 5

1.00

 

1.00

 

 ≥ 5

1.34 (0.61–3.10)

0.477

1.52 (0.68–3.61)

0.321

Geographical location

 Eastern

5.43 (2.04–18.81)

0.002

6.25 (2.02–23.55)

0.003

 Western

1.00

 

1.00

 

Endemicity

 Low transmission

1.00

 

1.00

 

 Moderate transmission

1.88 (0.86–4.08)

0.109

0.78 (0.32–1.91)

0.579

Parasite density (μL)

 <1000

1.12 (0.50–2.41)

0.782

0.97 (0.42–2.16)

0.943

 ≥1000

1.00

 

1.00

 

pfhrp2/pfhrp3+ gene deletions

Variable

Univariable

Multivariable

OR (95% CI)

p-value

aOR (95% CI)

p-value

Gender

Male

1.00

 

1.00

 

Female

1.10 (0.30–4.04)

0.881

0.89 (0.23–3.39)

0.862

Age (years)

 < 5

1.00

 

1.00

 

 ≥ 5

1.62 (0.44–7.65)

0.489

1.64 (0.43–7.92)

0.493

Geographical location

 Eastern

3.16 (0.78–21.18)

0.15

6.84 (1.50–48.30)

0.022

 Western

1.00

 

1.00

 

Endemicity

 Low transmission

1.00

 

1.00

 

 Moderate transmission

0.46 (0.07–1.88)

0.333

0.19 (0.03–0.88)

0.049

Parasite density (μL)

 < 1000

0.66 (0.14–2.43)

0.555

0.61 (0.13–2.30)

0.488

 ≥ 1000

1.00

 

1.00