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Table 4 Factors associated with pfhrp2/3 deletions (overall)

From: Molecular surveillance reveals the presence of pfhrp2 and pfhrp3 gene deletions in Plasmodium falciparum parasite populations in Uganda, 2017–2019

Variable Univariable Multivariable
OR (95% CI) p-value aOR (95% CI) p-value
Gender
 Male 1.00   1.00  
 Female 1.20 (0.55–2.60) 0.646 1.24 (0.55–2.80) 0.598
Age (years)
 < 5 1.00   1.00  
 ≥ 5 1.34 (0.61–3.10) 0.477 1.52 (0.68–3.61) 0.321
Geographical location
 Eastern 5.43 (2.04–18.81) 0.002 6.25 (2.02–23.55) 0.003
 Western 1.00   1.00  
Endemicity
 Low transmission 1.00   1.00  
 Moderate transmission 1.88 (0.86–4.08) 0.109 0.78 (0.32–1.91) 0.579
Parasite density (μL)
 <1000 1.12 (0.50–2.41) 0.782 0.97 (0.42–2.16) 0.943
 ≥1000 1.00   1.00  
pfhrp2/pfhrp3+ gene deletions
Variable Univariable Multivariable
OR (95% CI) p-value aOR (95% CI) p-value
Gender
Male 1.00   1.00  
Female 1.10 (0.30–4.04) 0.881 0.89 (0.23–3.39) 0.862
Age (years)
 < 5 1.00   1.00  
 ≥ 5 1.62 (0.44–7.65) 0.489 1.64 (0.43–7.92) 0.493
Geographical location
 Eastern 3.16 (0.78–21.18) 0.15 6.84 (1.50–48.30) 0.022
 Western 1.00   1.00  
Endemicity
 Low transmission 1.00   1.00  
 Moderate transmission 0.46 (0.07–1.88) 0.333 0.19 (0.03–0.88) 0.049
Parasite density (μL)
 < 1000 0.66 (0.14–2.43) 0.555 0.61 (0.13–2.30) 0.488
 ≥ 1000 1.00   1.00