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Fig. 5 | Malaria Journal

Fig. 5

From: Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose

Fig. 5

Immunization of rabbits with Pfs25 and Pfs230C1 elicits specific antibodies using duplexed and individual antigens with CoPoP liposomes. Rabbits were immunized with 20 μg of total Pfs25, Pfs230 or duplexed antigens with CoPoP/MPLA liposomes on day 0 and day 28, and final bleeding was collected on day 56. a Pfs25 and b Pfs230C1 ELISA IgG titre. ELISA experiments were performed with n = 4 of independent rabbits and line represent geometric mean. One-way ANOVA followed by Tukey test using log transformed data was used to compare difference. ****p < 0.0001

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