Table 5 Comparison of test performances between QuantiFast™ and abTES™ for detection of P. knowlesi, P. vivax, P. falciparum and P. malariae
Sensitivity (95% CI min, max) | Specificity (95% CI min, max) | ROC area (95% CI min, max) | Positive predictive value (PPV) (95% CI min, max) | Negative predictive value (NPV) (95% CI min, max) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QuantiFast™ | abTES™ | p-val | QuantiFast™ | abTES™ | p-val | QuantiFast™ | abTES™ | p-val | QuantiFast™ | abTES™ | p-val | QuantiFast™ | abTES™ | p-val | |
P. knowlesi (n = 52) | 98.1 (89.7, 100) | 100 (93.2, 100) | 0.32 | 98.8 (93.5, 100) | 98.8 (93.5, 100) | 1.0 | 0.98 (0.96, 1) | 0.99 (0.98, 1) | 0.46 | 98.1 (89.7, 100) | 98.1 (89.9, 100) | 0.56 | 98.8 (93.5, 100) | 100 (95.6, 100) | 0.56 |
P. vivax (n = 25) | 100 (86.3, 100) | 100 (86.3, 100) | 1.0 | 100 (96.7, 100) | 100 (96.7, 100) | 1.0 | 1.0 (1, 1) | 1.0 (1, 1) | 1.0 | 100 (86.3, 100) | 100 (86.3, 100) | 1.0 | 100 (96.7, 100) | 100 (96.7, 100) | 1.0 |
P. falciparum (n = 21) | 100 (83.9, 100) | 100 (83.9, 100) | 1.0 | 100 (96.8, 100) | 100 (96.8, 100) | 1.0 | 1 (1, 1) | 1 (1, 1) | 1.0 | 100 (83.9, 100) | 100 (83.9, 100) | 1.0 | 100 (96.8, 100) | 100 (96.8, 100) | 1.0 |
P. malariae (n = 10) | 90.0 (55.5, 99.7) | 100 (69.2, 100) | 0.32 | 100 (97.1, 100) | 100 (97.1, 100) | 1.0 | 0.95 (0.85, 1) | 1 (1, 1) | 0.32 | 100 (66.4, 100) | 100 (69.2, 100) | 0.32 | 99.2 (95.7, 100) | 100 (97.1, 100) | 0.32 |