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Table 5 Comparison of test performances between QuantiFast™ and abTES™ for detection of P. knowlesi, P. vivax, P. falciparum and P. malariae

From: Comparative evaluation of two commercial real-time PCR kits (QuantiFast™ and abTES™) for the detection of Plasmodium knowlesi and other Plasmodium species in Sabah, Malaysia

  Sensitivity (95% CI min, max) Specificity (95% CI min, max) ROC area (95% CI min, max) Positive predictive value (PPV) (95% CI min, max) Negative predictive value (NPV) (95% CI min, max)
QuantiFast™ abTES™ p-val QuantiFast™ abTES™ p-val QuantiFast™ abTES™ p-val QuantiFast™ abTES™ p-val QuantiFast™ abTES™ p-val
P. knowlesi
(n = 52)
98.1
(89.7, 100)
100
(93.2, 100)
0.32 98.8
(93.5, 100)
98.8
(93.5, 100)
1.0 0.98
(0.96, 1)
0.99
(0.98, 1)
0.46 98.1
(89.7, 100)
98.1
(89.9, 100)
0.56 98.8
(93.5, 100)
100
(95.6, 100)
0.56
P. vivax
(n = 25)
100
(86.3, 100)
100
(86.3, 100)
1.0 100
(96.7, 100)
100
(96.7, 100)
1.0 1.0
(1, 1)
1.0
(1, 1)
1.0 100
(86.3, 100)
100
(86.3, 100)
1.0 100
(96.7, 100)
100
(96.7, 100)
1.0
P. falciparum
(n = 21)
100
(83.9, 100)
100
(83.9, 100)
1.0 100
(96.8, 100)
100
(96.8, 100)
1.0 1
(1, 1)
1
(1, 1)
1.0 100
(83.9, 100)
100
(83.9, 100)
1.0 100
(96.8, 100)
100
(96.8, 100)
1.0
P. malariae
(n = 10)
90.0
(55.5, 99.7)
100
(69.2, 100)
0.32 100
(97.1, 100)
100
(97.1, 100)
1.0 0.95
(0.85, 1)
1
(1, 1)
0.32 100
(66.4, 100)
100
(69.2, 100)
0.32 99.2
(95.7, 100)
100
(97.1, 100)
0.32