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Table 4 Prediction performance measures of the final selected models

From: Evaluating the predictive performance of malaria antibodies and FCGR3B gene polymorphisms on Plasmodium falciparum infection outcome: a prospective cohort study

Model specification LR, p-value BCV AUROC (97.5% CI) BCV Brier score (%) R2 (%)
FMNS 25.91, 0.0176 57.49(45.38–68.38) 12.10 1.00
SCOV 31.08, 0.0175 58.38(45.38–68.72) 12.00 2.00
NBC 22.41, 0.0077 61.51(48.87–70.71) 11.72 4.00
  1. FMNS = PMLE.model + logIgGAMA1 + logIgG1AMA1 + dominant c.233 with 5 knots restricted cubic spline, Model SCOV = Slope Corrected final model with van Houwelingen-Le Cessie heuristic estimate
  2. NBC = No baseline variable included: only dominant c.233 + logIgGAMA1 + logIgG1AMA1
  3. LR, BCV, RMSE, R2, AUROC, BS, represent the Likelihood Ratio test statistic, bootstrap cross-validation, Root Mean Squared Error, the proportion of explained variation in predicted risk and Area Under the Receiver Operating Characteristic curve, Brier score, respectively