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Table 1 18S rRNA quantification of liver parasite burden by lobe following intravenous inoculation of PfSPZ or PkSPZ

From: Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

Animal Group LLL LML RLL RML + C Avg* Age Sex Weight (kg) CRP (mg/L)
A18156 P. falciparum (1 × 106) N.D N.D N.D N.D N.D 1 year 6 months Female 2.7 0.5
A18153 P. falciparum (1 × 106) 5.31 5.73 5.35 5.88 5.57 1 year 6 months Male 2.35 < 0.2
A18155 P. falciparum (5 × 106) N.D N.D 5.73 4.91 5.32 1 year 6 months Female 2.4 0.3
A18151 P. falciparum (5 × 106) 6.02 6.35 6.11 6.61 6.27 1 year 6 months Male 2.9 0.2
A18152 P. knowlesi (0.5 × 106) 9.69 9.30 9.61 9.47 9.52 1 year 6 months Male 3.15 0.2
A18154 P. knowlesi (0.5 × 106) 10.09 9.53 9.82 9.45 9.72 1 year 7 months Male 1.95 0.7
  1. P. falciparum data reported in log10 copies of 18S rRNA/g tissue as detected by the P. falciparum target. P. knowlesi data reported in log10 copies of 18S rRNA/g tissue as detected by the Pan Plasmodium target
  2. LML left medial lobe, RLL right lateral lobe, LLL left lateral lobe, RML + C right medial lobe and caudate lobe, CRP C-reactive protein, N.D not detected, F female, M male, Avg* mean of samples where Plasmodium 18S rRNA was detected