From: The clinical spectrum of severe childhood malaria in Eastern Uganda
Variable | Univariate logistic regression | Multivariate logistic regression | ||
---|---|---|---|---|
Odds ratio (95%CI) | P-value | Odds ratio (95%CI) | P-value | |
Clinical | ||||
 Pyrexia | 0.56 (0.33–0.94) | 0.027 | 0.79 (0.40–1.57) | 0.50 |
 Pallor | 2.61 (1.48–4.61) | 0.001 | 0.84 (0.34–2.12) | 0.98 |
 Coma | 4.94 (1.20–20.2) | 0.01 | 1.52 (0.28–8.23) | 0.62 |
 Delayed capillary refill | 2.13 (1.21–3.73) | 0.007 | 0.82 (0.35–1.93) | 0.64 |
 Splenomegaly | 1.72 (1.02–2.89) | 0.040 | 1.00 (0.46–2.18) | 0.75 |
 Hepatomegaly | 1.98 (1.17–3.33) | 0.009 | 2.29 (1.29–4.06) | 0.004 |
 Hypoxaemia | 4.60 (2.32–9.13) | 1.25 × 10−5 | 3.64 (1.39–9.52) | 0.008 |
Laboratory | ||||
 Severe anaemia | 3.74 (2.20–6.36) | 1.05 × 10−6 | 5.36 (2.16–1.32) | 0.0002 |
 Hyperlactataemia | 5.83 (3.40–9.50) | 1.58 × 10−7 | 3.66 (1.72–7.80) | 0.001 |
 Hypoglycaemia | 3.84 (1.44–10.19) | 0.004 | 2.25 (0.63–7.98) | 0.21 |
 Leucocytosis | 1.79 (1.04–3.09) | 0.035 | 1.03 (0.49–2.14) | 0.93 |