Table 2 Summary of pmcrt gene polymorphisms in Thailand and Myanmar
Prevalence of Pmcrt polymorphism | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Countries | Areas | N | Non-synonymous mutation | Synonymous mutation | |||||||
Exon 2 | Exon 8 | Exon 2 | Exon 2 | Exon 2 | Exon 2 | Exon 9 | Exon 10 | Exon 12 | |||
A363C CAT > CCT H53P | A2120T GAA > GAT E278D | C346T F47F | C353T L50L | C394G T63T | A403T I66I | T2483C N300N | T2637A L319L | A3151T I375I | |||
Thailand | Kanchanaburia | 6 | 50% (3/6) | 50% (3/6) | 33% (2/6) | 66.66% (4/6) | 0% (0/6) | 50% (3/6) | 1.05% (1/6) | 0% (0/6) | 1.05% (1/6) |
Thailand | Cheangmaib | 1 | 0% (0/1) | 100% (1/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) |
Thailand | Takc | 44 | 70.45% (31/44) | 61.36% (27/44) | 31.81% (14/44) | 61.36% (27/44) | 0% (0/44) | 47.72% (21/44) | 0% (0/44) | 0% (0/44) | 9.09% (4/44) |
Thailand | Total | 51 | 66.66% (34/51) | 60.78% (31/51) | 31.37% (16/51) | 60.78% (31/51) | 0% (0/51) | 47.05% (24/51) | 1.96% (1/51) | 0% (0/51) | 9.80% (5/51) |
Myanmar | Totald | 44 | 9.09% (4/44) | 25% (11/44) | 4.54% (2/44) | 45.45% (20/44) | 9.09% (4/44) | 6.81% (3/44) | 2.27% (1/44) | 2.27% (1/44) | 2.27% (1/44) |
Total in Thailand and Myanmar N = 95 | 40% (38/95) | 44.21% (42/95) | 18.94% (18/95) | 53.68% (51/95) | 4.21% (4/95) | 28.42% (27/95) | 2.10% (2/95) | 1.05% (1/95) | 6.31% (6/95) | ||