Table 4 Summary of pmmdr1 gene polymorphisms in Thailand and Myanmar
Prevalence of pmmdr1 polymorphism | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Countries | Areas | N | Non-synonymous mutation | Synonymous mutation | |||||||||||
NT 17 AAC > ATC N6I | NT 20 TAT > TGT Y7C | NT 1468 CTT > ATT L490I | NT 3189 TTA > TTC L1063F | NT 3743 AAC > ATC N1248I | NT 3796 ACA > TCA T1266S | NT 4083 AGA > AGT R1361S | NT 4216 ACT > TCT T1406S | NT 4378 GCC > TCC A1460S | NT 4378 GCC > ACC A1460T | NT 231 TCC > TCT S77S | NT 1389 AGC > AGT S463S | NT 1845 TTG > TTA L615L | |||
Thailand | Kanchanaburia | 6 | 0% (0/6) | 0% (0/6) | 0% (0/6) | 66.66% (4/6) | 0% (0/6) | 0% (0/6) | 1.05% (1/6) | 1.05% (1/6) | 0% (0/6) | 0% (0/6) | 0% (0/6) | 83.33% (5/6) | 33% (2/6) |
Cheangmaib | 1 | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 0% (0/1) | 100% (1/1) | 100% (1/1) | |
Takc | 44 | 4.54% (2/44) | 4.54% (2/44) | 0% (0/44) | 27.27% (12/44) | 0% (0/44) | 2.27% (1/44) | 2.27% (1/44) | 2.27% (1/44) | 0% (0/44) | 0% (0/44) | 18.18% (8/44) | 31.81% (14/44) | 25% (11/44) | |
Total | 51 | 3.92% (2/51) | 3.92% (2/51) | 0% (0/51) | 31.37% (16/51) | 0% (0/51) | 1.96% (1/51) | 3.92% (2/51) | 3.92% (2/51) | 0% (0/51) | 0% (0/51) | 15.68% (8/51) | 39.21% (20/51) | 27.45% (14/51) | |
Myanmar | Totald | 4 | 0% (0/44) | 6.81% (3/44) | 9.09% (4/44) | 0% (0/44) | 11.36% (5/44) | 25% (11/44) | 2.27% (1/44) | 4.54% (2/44) | 9.09% (4/44) | 4.54% (2/44) | 0% (0/44) | 45.45% (20/44) | 36.36% (16/44) |
Total in Thailand and Myanmar N = 95 | 2.10% (2/95) | 5.26% (5/95) | 4.21% (4/95) | 16.84% (16/95) | 5.26% (5/95) | 12.63% (12/95) | 3.15% (3/95) | 4.21% (4/95) | 4.21% (4/95) | 2.10% (2/95) | 8.42% (8/95) | 42.10% (40/95) | 31.57% (30/95) | ||