Table 3 Sensitivity, specificity, positive and negative predictive values of RDT, routine Microscopy, MG-LAMP and expert microscopy using RT-PCR as reference
Method | Sensitivity, % (CI) | Specificity, % (CI) | PV, % (CI) | NPV, % (CI) | K-value, % (CI) |
|---|---|---|---|---|---|
Rota dispensary | |||||
 RDT | 78.1 (67.5–86.4) | 93.0 (86.8–97) | 88.9 (79.3–95.1) | 85.6 (78.2–91.2) | 0.72 (0.59–0.86) |
 MG-LAMP | 82.9 (73.0–90.3) | 83.5 (75.4–89.8) | 78.1 (68.0–86.3) | 87.3 (79.6–92.9) | 0.66 (0.52–0.80) |
 E-microscopy | 72.0 (61–81.3) | 100 (96.8–100) | 100 (93.9–100) | 83.3 (78–87.6) | 0.75 (0.61–0.88) |
Siaya Hospital | |||||
 R-microscopy | 83.3 (65.3–94.4) | 91.9 (78.1–98.3) | 89.3 (71.8–97.7) | 87.2 (72.6–95.7) | 0.76 (0.52–1.00) |
 MG-LAMP | 93.3 (77.9–99.2) | 73.0 (55.9–86.2) | 73.7 (56.9–86.6) | 93.1 (77.2–99.2) | 0.65 (0.41–0.88) |
 E-microscopy | 86.7 (69.3–96.2) | 91.9 (78.1–98.3) | 89.7 (74.4–96.3) | 89.5 (77.3–95.5) | 0.79 (0.55–1.03) |