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Table 1 Characteristics of ITT clinical trial population

From: An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

Variable

Chloroquine-azithromycin CQ/AZ (N = 15)

Chloroquine (CQ) (N = 8)

All subjects (N = 23)

Age (years)

 n

15

8

23

 Mean (SD)

30.6 (6.38)

33.5 (6.78)

31.6 (6.52)

 Median

31.0

35.0

32.0

 Min, max

21, 43

23, 41

21, 43

 Two sample t-test p-value

0.3209

  

Gender: n (%)

 Male

8 (53.3%)

3 (37.5%)

11 (47.8%)

 Female

7 (46.7%)

5 (62.5%)

12 (52.2%)

 Undifferentiated

0

0

0

 Fisher’s exact test p-value

0.6668

  

Ethnicity: n(%)

 Hispanic or Latino

1 (6.7%)

1 (12.5%)

(8.7%)

 Not hispanic or latino

14 (93.3%)

7 (87.5%)

(91.3%)

 Fisher’s exact test p-value

> 0.9999

  

Race: n (%)

 American Indian or Alaska

0

0

0

 Asian

2 (13.3%)

0

2 (8.7%)

 Black or African American

3 (20.0%)

1 (12.5%)

4 (17.4%)

 Native Hawaiian or Other Islander

0

0

0

 White

9 (60.0%)

5 (62.5%)

(4 60.9%)

 Other

0

0

0

Multi-racial

1 (6.7%)

2 (25.0%)

3 (13.0%)

 Fisher’s exact test

0.6815

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