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Table 2 Microscopic parasitemia results

From: An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

 

Chloroquine-Azithromycin CQ/AZ (N = 12)1

Chloroquine (CQ) (N = 6)

Parasitemia

 n (%)

7 (58)

6 (100)

Symptomatic parasitemia

 n (%)

5 (42)

6 (100)

Symptomatic parasitemia during post-exposure prophy period2

 n (%)

1 (8)

6 (100)

Days to Parasitemia3

  Mean (range)

31 (9–41)

13 (10–15)

  1. 1Efficacy population defined as received all 3 doses of pre-exposure prophylaxis, malaria challenged and received at least one dose of post-exposure prophylaxis
  2. 21-28 days after malaria challenge
  3. 3Days after malaria challenge
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Malaria Journal

ISSN: 1475-2875

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