|
Variables
|
Symptomatic N = 25
|
Asymptomatic N = 67
|
Uninfected control N = 16
|
P value
|
|---|
|
Age (years)
|
9 (7–12)
|
9(8–11)
|
10 (8.25–11)
|
0.7621a
|
|
Gender (%), Female/Male
|
48/52
|
43/57
|
62/38
|
0.3830b
|
|
Parasite density (/µl),
|
13,893 (4762–36,300)
|
400(160–630)20
|
NA
|
< 0.0001c
|
|
PfHRP2 (ng/ml)
|
291.6 (7.87–1100)22
|
6.44 (2.42—12.73)29
|
NA
|
< 0.0001c
|
|
Haematological indices
|
|
Haemoglobin (g/dl)
|
11.00 (8.50–12.00)
|
10.70 (10.00–12.00)
|
11.70 (10.33–12.88)
|
0.0828a
|
|
WBC (× 109/l)
|
6.60 (4.93–7.99)
|
6.20 (4.82–7.38)
|
6.98(6.20–8.73)
|
0.2511a
|
|
Neutrophils (× 109/l)
|
4.3 (3.04–5.70)
|
1.84(1.40–2.30)
|
1.84(0.87–2.55)
|
< 0.0001a
|
|
Neutrophils (%)
|
69.90 (61.45–78.25)
|
29.50 (23.50–38.70)
|
25.35 (21.63–32.18)
|
< 0.0001a
|
|
Lymphocytes (× 109/l)
|
1.00 (0.70–1.86)
|
3.37 (2.59–4.30)
|
4.19 (3.13–4.58)
|
< 0.0001a
|
|
Lymphocytes (%)
|
17.90 (11.20–28.75)
|
55.90 (47.60–67.68)
|
59.00 (49.00–67.68)
|
< 0.0001a
|
|
Monocytes (× 109/l)
|
0.40 (0.24–0.65)
|
0.52(0.34–0.72)
|
0.52 (0.44–0.62)
|
0.3366a
|
|
Monocytes (%)
|
7.30 (3.95–10.47)
|
8.10 (6.40–10.70)
|
8.00 (6.83–9.13)
|
0.4395a
|
|
Platelets (× 109/l)
|
109 (59.0–144.0)
|
264 (205.0–334.0)
|
241.0 (204.8–334.8)
|
< 0.0001a
|
- PfHRP2 P. falciparum histidine-rich protein 2; WBC white blood cell count. Data are median [interquartile range (IQR)], and superscripts indicate the number of subjects with data for each variable if less than the total. aKruskal–Wallis test, bChi-square test, cMann–Whitney U test
