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Fig. 4 | Malaria Journal

Fig. 4

From: Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation

Fig. 4

Binding of non-immune IgM and α2M to P. falciparum-infected erythrocytes. a Representative flow cytometry histograms of field isolates from children with uncomplicated malaria (UM) and severe malaria (SM) in the presence of non-immune IgM (above) and α2M (below). b Binding of non-immune IgM (above) and α2M (below) to IEs from children with UM (closed symbols, n = 14) and SM (open symbols, n = 20) at 1 nM (p = 0.24 and p = 0.15), 10 nM (p = 0.07 and p = 0.07), and 100 nM (p = 0.15 and p = 0.06), respectively. A laboratory clone, HB3VAR06, it is included for comparison. Medians and interquartile ranges are shown. p value between UM and SM using Mann–Whitney test. Two independent experiments were done at each concentration

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Malaria Journal

ISSN: 1475-2875

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