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Fig. 1 | Malaria Journal

Fig. 1

From: Plug for the parasitophorous duct: a solution of two conundra

Fig. 1

Proposed model for formation of parasitophorous duct plug. a Formation of tight junction (black rectangle) between merozoite apical and red blood cell (RBC) membranes. b Location of tight junction during entry of merozoite into RBC interior. c Parasitophorous duct plug formed from tight junction located at orifice of parasitophorous vacuole upon completion of merozoite ingress. d Disruption of parasitophorous duct plug by merozoite protease(s) to form opening on RBC surface for progeny merozoites release. M, merozoite; P, parasitophorous duct plug; PD, parasitophorous duct; PVM, parasitophorous vacuolar membrane; RBCM, red blood cell membrane

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