Fig. 6

Differential activation of HBMVEC by co-culture with CM parasite lines is reduced by DMF pretreatment. a IL-6 concentrations were measured by ELISA in the supernatants of HBMVEC stimulated by direct contact with P. falciparum-IE from 8 CM parasite lines, IT4var19, and uninfected red blood cells (RBC) at IE:HBMVEC ratio of 12:1 for 24 h. b IL-6 levels of HBMVEC supernatants co-cultured with IE for 24 h with or without 1 h DMF pretreatment (n = 2 independent experiments in triplicate). Results were analysed using analysis of variance followed by post-hoc multiple comparisons using Turkey’s test. **p < 0.01. Bars depict the mean with SEM