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Table 1 Differentially expressed HBMVEC transcripts in DMF pretreated TNF activated compared to TNF activated cells

From: Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro

Gene symbol Description Fold change FDR p-value
STC1 Stanniocalcin 1 58 2.27E−07
SRXN1 Sulfiredoxin 1 8 6.99E−06
RGCC Regulator of cell cycle 7 7.28E−07
HMOX1 Heme oxygenase 1 6 1.66E−05
NID2 Nidogen 2 (osteonidogen) 5 4.89E−06
OSGIN1 Oxidative stress induced growth inhibitor 1 5 2.88E−06
SLC16A6 Solute carrier family 16, member 6 5 7.07E−06
AHR Aryl hydrocarbon receptor 4 9.25E−06
CCRL2 Chemokine (C–C motif) receptor-like 2 3 7.18E−05
CLDN14 Claudin 14 3 0.0022
VCAM1 Vascular cell adhesion molecule 1 − 488 9.19E−10
TNFAIP6 Tumor necrosis factor, alpha-induced protein 6 − 42 7.56E−08
SELE Selectin E − 20 9.64E−07
IL18R1 Interleukin 18 receptor 1 − 9 4.46E−06
OAS1 2–5-Oligoadenylate synthetase 1 − 9 2.53E−06
ICAM1 Intercellular adhesion molecule 1 − 6 5.61E−06
LTB Lymphotoxin beta (TNF superfamily) − 4 7.93E−06
NALCN Sodium leak channel, non selective − 4 0.0001
IL-6 Interleukin 6 − 3 0.0002
IL1R1 Interleukin 1 receptor, type I − 3 0.0024
  1. Selected transcripts shown. Fold change was calculated as the average between groups of log2-transformed data