Table 1 Differentially expressed HBMVEC transcripts in DMF pretreated TNF activated compared to TNF activated cells
Gene symbol | Description | Fold change | FDR p-value |
|---|---|---|---|
STC1 | Stanniocalcin 1 | 58 | 2.27E−07 |
SRXN1 | Sulfiredoxin 1 | 8 | 6.99E−06 |
RGCC | Regulator of cell cycle | 7 | 7.28E−07 |
HMOX1 | Heme oxygenase 1 | 6 | 1.66E−05 |
NID2 | Nidogen 2 (osteonidogen) | 5 | 4.89E−06 |
OSGIN1 | Oxidative stress induced growth inhibitor 1 | 5 | 2.88E−06 |
SLC16A6 | Solute carrier family 16, member 6 | 5 | 7.07E−06 |
AHR | Aryl hydrocarbon receptor | 4 | 9.25E−06 |
CCRL2 | Chemokine (C–C motif) receptor-like 2 | 3 | 7.18E−05 |
CLDN14 | Claudin 14 | 3 | 0.0022 |
VCAM1 | Vascular cell adhesion molecule 1 | − 488 | 9.19E−10 |
TNFAIP6 | Tumor necrosis factor, alpha-induced protein 6 | − 42 | 7.56E−08 |
SELE | Selectin E | − 20 | 9.64E−07 |
IL18R1 | Interleukin 18 receptor 1 | − 9 | 4.46E−06 |
OAS1 | 2–5-Oligoadenylate synthetase 1 | − 9 | 2.53E−06 |
ICAM1 | Intercellular adhesion molecule 1 | − 6 | 5.61E−06 |
LTB | Lymphotoxin beta (TNF superfamily) | − 4 | 7.93E−06 |
NALCN | Sodium leak channel, non selective | − 4 | 0.0001 |
IL-6 | Interleukin 6 | − 3 | 0.0002 |
IL1R1 | Interleukin 1 receptor, type I | − 3 | 0.0024 |