Dimethyl fumarate reduces TNF and Plasmodium falciparum induced brain endothelium activation in vitro

Malaria Journal

Table 2 Description of children with CM where P. falciparum lines were derived

Parasite line	Retinopathy status	Blantyre coma score	Coma duration (h)	Brain swelling score (MRI^a)	Parasitemia (IE/µl)	HCT (% volume)
3173	Ret+	2	36	5	148,500	19
3180	Ret+	2	16	3	296,000	32
3194	Ret+	2	20	ND	177,120	23
3207	Ret+	1	108	3	632,500	21
3080	Ret+	2	56	5	520	21
3005	Ret−	2	24	ND	20,500	25
3013	Ret−	1	10	3	45,000	25
3039	Ret−	2	12	ND	600,000	25

Ret retinopathy, HCT hematocrit, ND not done
^aMRI scores for brain swelling (scale 1–8): 1–4: absence of swelling, 5–6: mild/moderate swelling; 7–8: severe swelling

ISSN: 1475-2875