Fig. 1

a Protein sequence with predicted features. Residues highlighted in yellow constitute CSD while residues in red and green denote those involved in DNA binding and RNA binding, respectively. b Schematic representation of domain organization and interaction sites in PfCoSP (c) Graph shows transcriptome data of PfCoSP. X-axis denotes P. falciparum 7 life-cycle stages and Y-axis represent transcript levels of fragments per kilobase of exon model per million mapped reads (FPKM). d Multiple sequence alignment of PfCoSP with its homologues in Escherichia coli, Homo sapiens and plants (Vitis vinifera, Rhodamnia argentea). Predicted residues involved in DNA and RNA binding in PfCoSP and their corresponding residues in other family members are marked in yellow and green bars, respectively. e Phylogenetic tree of PfCoSP with its homologues in Escherichia coli, Homo sapiens and plants (Vitis vinifera, Rhodamnia argentea)