Pleiotropic roles of cold shock proteins with special emphasis on unexplored cold shock protein member of Plasmodium falciparum

Table 3 Identified motifs in PfCoSP using MEME tool and their matched sequences found in protein sequence database by find individual motif occurrence (FIMO)

	Matched sequence by FIMO	Protein family	Biological function
1	WNFAYDITQ	Site specific DNA methytransferases	They catalyze the transfer of a methyl group to DNA. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression
2	LVRGIR	Phosphatidylinositol 4-kinases	Catalyzes phosphorylation of phosphatidylinositol (PI) at the D-4 position, yielding phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in Golgi function, protein sorting and membrane trafficking. Besides, phosphorylation of PI to PI4P is the first step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate
3	HFNRYL	Homeobox proteins	Homeobox genes encode homeodomain protein products that bind DNA to regulate expression of target genes

Significant matches of proteins/enzymes for these motifs are mentioned along with their biological function

ISSN: 1475-2875