Genetic variations in histidine-rich protein 2 and histidine-rich protein 3 of Myanmar Plasmodium falciparum isolates

Table 1 The amino acid changes identified in repeat types in Myanmar pfhrp2 and pfhrp3

Gene	Types	Variants	Frequency (%)
pfhrp2	Type 1 AHHAHHVAD	AHHAHHVAY	1.17
		AHRAHHVAD*	1.17
		AHHARHVAD*	1.17
		AHPAAHVAD*	1.17
		AHHAHHEAD*	1.17
		ARHAHHVAD*	1.17
	Type 2 AHHAHHAAD	VHHAHHAAD*	1.17
		AHHAHHAAG	2.35
		AHHAHHTAD	1.17
		AHHARHAAD*	1.17
		AHHTHHAAD	2.35
		ARHAHHAAD	1.17
	Type 6 AHHATD	VHHATD*	1.17
		AHHAID*	1.17
		DHHATD*	1.17
		AHHAPD	1.17
	Type 7 AHHAAD	HHAAD*	1.17
	Type 7 AHHAAD	AHHAAA*	1.17
pfhrp3	Type 16 AHHAAN	AHHASN	1.78
	Type 18 AHHAAD	ARHAAD*	1.78
	Type 20 SHHDD	SYHDD*	1.78

The amino acid changes are presented as bold. Asterisks indicate novel variants that have not been reported previously. The – in type 6 of pfhrp2 means a deletion of alanine (A) at the corresponding position. Frequency means percentage of sequences with the corresponding repeat type variant in Myanmar pfhrp2 or pfhrp3

ISSN: 1475-2875