Table 1 Diagnostic performance of vivax malaria and dengue fever flags

Nsamples

1422

1341

412

202

Vivax malaria

ROC AUC

0.902 [0.880–0.924]

0.902 [0.880–0.924]

0.900 [0.877—0.923]

0.901 [0.868—0.933]

cut-off 0.5

Sensitivity

65.2% [60.2–69.9%]

65.2% [60.2–69.9%]

65.2% [60.2–69.9%]

65.2% [60.2–69.9%]

Specificity

98.9% [98.5–99.3%]

99% [98.5–99.3%]

98.2% [96.6–99.1%]

100% [90.4 – 100%]

PPV

90.2% [86.2–93.2%]

91.3% [87.3–94.0%]

96.8% [93.8–98.4%]

100% [ -]

NPV

95% [94.3–95.6%]

94.7% [94.0–95.4%]

77.8% [75.3–80.1%]

22% [19.6–24.4%]

Younden

0.642

0.642

0.635

0.652

cut-off 0.31

Sensitivity

72.0% [67.2–76.4%]

72.0% [67.2–76.4%]

72.0% [67.2–76.4%]

72.0% [67.2–76.4%]

Specificity

97.9% [97.3–98.4%]

98% [97.4–98.5%]

96.9% [94.9–98.2%]

100% [90.4 – 100%]

PPV

83.9% [79.7–87.3%]

85.2% [81.1–88.5%]

95.0% [91.8–97.0%]

100% [ -]

NPV

95.9% [95.2–96.5%]

95.6% [94.9–96.3%]

81.1% [78.4–83.5%]

25.9% [22.9–29.2%]

Younden

0.699

0.700

0.689

0.720

Dengue

ROC AUC

0.814 [0.793–0.834]

0.808 [0.787–0.829]

0.904 [0.883–0.926]

-

cut-off 0.5

Sensitivity

79.3% [75.2–82.9%]

80.0% [75.9–83.5%]

79.3% [75.2–82.9%]

-

Specificity

71.6% [69.8–73.3%]

70.1% [68.1–71.9%]

86.4% [82.7–89.5%]

-

PPV

33.0% [31.3–34.8%]

33.2% [31.5–35.0%]

86.2% [82.9–89.0%]

-

NPV

95.2% [94.2–96.0%]

95.0% [93.9–95.8%]

79.6% [76.4–82.5%]

-

Younden

0.509

0.501

0.658

-