Characterisation of plasmodial transketolases and identification of potential inhibitors: an in silico study

Malaria Journal

Table 1 Quality evaluation scores of PTKT protein structures modeled

Protein	Modeller	ProSA		QMEAN6	Verify3D (%)	PROCHECK (%)
	Z-DOPE score	z-Score monomers		QMEAN score	3D-1D score	Ramachandran (residues location)
	Z-DOPE score	A	B	QMEAN score	3D-1D score	Favoured	Allowed	Disallowed
*1TRK	− 2.01	− 12.93	− 12.87	0.94	92.00	89.20	10.80	0.00
PfTKT	− 1.39	− 12.11	− 12.01	0.77	91.67	90.10	9.80	0.00
PvTKT	− 1.40	− 12.33	− 12.25	0.77	91.34	88.30	10.90	0.10
PoTKT	− 1.35	− 11.28	− 11.27	0.76	84.30	88.40	10.90	0.20
PmTKT	− 1.29	− 11.23	− 11.20	0.75	84.85	87.30	11.90	0.20
PkTKT	− 1.35	− 11.58	− 11.48	0.77	85.10	89.20	9.80	0.30

ISSN: 1475-2875