Fig. 3
From: Cryptic Plasmodium chronic infections: was Maurizio Ascoli right?
Cryptic Plasmodium infections. The scheme represents potential dormant Plasmodium niches in the liver (P. vivax hypnozoites), as well as in the bone marrow and the spleen (Plasmodium-infected red blood cells). In the upper left square, anti-vir immuno-histochemistry of a spleen section with stained P. vivax parasites is shown. According to Ascoli’s theory, after the injection of adrenaline parasites were released in the peripheral circulation. After treatment, the spleen returns to its normal size, parasitaemia is no longer seen and the haematocrit increases back to normal levels