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Table 1 Characteristics of study participants

From: Infant sex modifies associations between placental malaria and risk of malaria in infancy

Characteristic

Maternal IPTp arm

Monthly SP (N = 327)

Monthly DP (N = 329)

Maternal characteristics at enrolment

 Age in years, mean (SD)

24.0 (5.9)

24.0 (5.7)

 Gravidity, n (%)

  Primigravida/secundigravida

152 (46.5%)

156 (47.4%)

  Multigravida

175 (53.5%)

173 (52.6)

 House-hold type, n (%)

  Modern House

77 (23.6%)

71 (21.6%)

  Traditional House

250 (76.5%)

258 (78.4%)

 Parasite prevalence by microscopy or qPCR, n (%)

  No parasites

53 (16.2%)

63 (19.2%)

  Sub-microscopic parasitaemia

111 (33.9%)

88 (26.8%)

  Microscopic parasitaemia

163 (49.9%)

178 (54.1%)

Maternal characteristics during pregnancy

 Parasite prevalence by microscopy, n/N (%)a

797/2212 (36.0%)

355/2260 (15.7%)

 Incidence of malaria (episodes/ppy)

0.59

0.09

Placental malaria status

 Placental malaria status, n (%)

  No PM

119 (36.4%)

232 (70.5%)

  Active PM

71 (21.7%)

7 (2.1%)

  Past PM (Mild-moderate pigment)

97 (29.7%)

84 (25.5%)

  Past PM (Severe pigment)

40 (12.2%)

6 (1.8%)

  Characteristics of infants at birth

  Preterm birth, n (%)

25 (7.7%)

17 (5.2%)

  Gestation age in weeks, mean (SD)

39.4 (1.9)

39.6 (1.6)

  Low birth weight, n (%)

33 (10.1%)

25 (7.6%)

  Birth weight in grams, mean (SD)

3055 (505)

3024 (409)

  Female sex, n (%)

161 (49.2%)

175 (53.2%)

  1. SP Sulfadoxine–pyrimethamine, DP dihydroartemisinin–piperaquine, SD standard deviation, ppy per person year, qPCR quantitative polymerase chain reaction
  2. aDefined as number of routine positive blood smears divided by total number of routine blood smears
  3. No PM no parasites or pigment detected, active PM parasites detected with or without pigment, Past PM (Mild-moderate)  > 0–20% of high-power fields with pigment but no parasites, Past PM (severe) > 20%–60% of high-power fields with pigment but no parasites