Table 1 Frequency distribution of pfdhfr and pfdhps point mutations for P. falciparum isolates from Jazan, Saudi Arabia (n = 151)
Markera | Number | % |
|---|---|---|
Pfdhfr | ||
A16V | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
C50R | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
N51I | ||
Wild | 23 | 15.2 |
Mutated | 128 | 84.8 |
C59R | ||
Wild | 94 | 62.3 |
Mutated | 57 | 37.7 |
S108N | ||
Wild | 23 | 15.2 |
Mutated | 128 | 84.8 |
I164L | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
Pfdhps | ||
S436A/F | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
A437G | ||
Wild | 66 | 43.7 |
Mutated | 85 | 56.3 |
K540E | ||
Wild | 73 | 48.3 |
Mutated | 78 | 51.7 |
A581G | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
A613T/S | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |
I640F | ||
Wild | 151 | 100 |
Mutated | 0 | 0 |