| Children < 5 years (n = 295) | Children ≥ 5 years of age (n = 89) |
---|---|---|
Admission characteristics | ||
 Age (years), mean (SD) | 2.9 (0.9) | 6.5 (1.6) |
 Gender (male), n (%) | 172 (58.3) | 60 (67.4) |
 Weight-for-age z-score, mean (SD) | − 1.2 (1.1) | − 1.1 (1.0) |
 Height-for-age z-score, mean (SD) | − 1.3 (1.5) | − 0.8 (1.2) |
 Socio-economic status, mean (SD) | 9.1 (3.0) | 10.1 (3.2) |
 HOME z-score, mean (SD) | − 0.08 (1.04) | − 0.08 (0.88) |
Maternal education, n (%) | ||
 Primary 6 or lower | 114 (38.6) | 29 (32.6) |
 Primary 7 | 63 (21.4) | 20 (22.5) |
 Secondary or higher | 109 (37.0) | 36 (40.5) |
 Unknown | 9 (3.1) | 4 (4.5) |
Paternal education, n (%) | ||
 Primary 6 or lower | 62 (21.0) | 10 (11.2) |
 Primary 7 | 44 (14.9) | 18 (20.2) |
 Secondary or higher | 133 (45.1) | 41 (46.1) |
 Unknown | 56 (19.0) | 20 (22.5) |
HIV infected, n (%) | 6 (2.1) | 3 (3.4) |
Sickle cell status, n (%) | ||
 HbAA | 286 (97.3) | 78 (87.6) |
 HbAS | 2 (0.7) | 1 (1.1) |
 HbSS | 6 (2.0) | 10 (11.2) |
Admission severe malaria criteria | ||
 Cerebral malaria, n (%) | 145 (49.2) | 52 (58.4) |
 Deep breathing, n (%) | 19 (6.4) | 2 (2.3) |
 Repeated convulsions, n (%) | 102 (34.6) | 27 (30.3) |
 Prostration, n (%) | 215 (72.9) | 63 (70.8) |
 Shock, n (%) | – | – |
 Bleeding, n (%) | 2 (0.7) | 1 (1.1) |
 Jaundice, n (%) | 197 (66.8) | 51 (57.3) |
 Severe malarial anaemia, n (%) | 187 (63.4) | 40 (44.9) |
 Hypoglycaemia on admission, n (%) | 19 (6.6) | 1 (1.2) |
 Lactic acidosis, n (%) | 117 (42.2) | 19 (24.1) |
 Acute kidney injury, n (%) | 102 (34.6) | 28 (31.5) |
 Hyperparasitaemia, n (%) | 54 (19.0) | 12 (13.6) |
 Number of SM criteria present, mean (SD) | 3.9 (1.6) | 3.3 (1.2) |
Neurocognitive follow-up visits, n tested | Children < 5 years | Children ≥ 5 years |
---|---|---|
One week post-discharge, n tested | 257 | 86 |
Six months follow-up, n tested | 253 | 98 |
12Â months follow-up, n tested | 225 | 129 |
24Â months follow-up, n tested | 148 | 209 |
Total for any follow-up visits, n tested | 295 | 218 |
Admission Angpt-2 (median, IQR), ng/mL | 1.78 (0.99, 3.13) | 1.65 (0.84, 3.06) |