Fig. 4

a Superimposition of redocked P2FE-400 (shown as a solid line) with its original position (shown in ball-stick model) as a complex (co-crystal) in the binding site of the crystal structure of plasmepsin II (PDB 4cku). b Surface representation showing chloroquine in the binding site of plasmepsin II with lipophilicity coloring, white representing hydrophobic pockets and blue representing hydrophilic pockets. Chloroquine is shown in ball-stick model