Molecular characterization of G6PD mutations reveals the high frequency of G6PD Aures in the Lao Theung population

Table 1 Prevalence and frequency of G6PD gene mutations in the Lao Theung ethnic group

Mutation	Normal			Intermediate			G6PD deficient			Prevalence (%)	Frequency (95% Confidence interval)
	M (n = 73)	F (n = 160)		M (n = 0)	F (n = 15)^b		M (n = 5)	F (n = 4 )
	Hemi-zygotes	Homo-zygotes	Hetero-zygotes	Hemi-zygotes	Homo-zygotes	Hetero-zygotes	Hemi-Zygotes	Homo-zygotes	Hetero-zygotes
Viangchan c.871G > A with nt1311T	0	0	0	0	0		1	0	0	1 (0.40)	0.0023 0.0001–0.0130
Jammu c.871G > A with nt1311C	0	0	1	0	0	1	0	0	0	2 (0.79)	0.0047 0.0006–0.0169
Mahidol c.487G > A	0	0	0	0	0	1	0	1	0	2 (0.79)	0.0070 0.0015–0.0204
Union c.1360C > T	0	0	1	0	0	1	1	0	0	3 (1.19)	0.0070 0.0015–0.0204
Kaiping c.1388G > A	0	0	0	0	0	1	1	0	0	2 (0.79)	0.0047 0.0006–0.0169
Canton c.1376G > T	0	0	1	0	0	0	0	0	0	1 (0.40)	0.0023 0.0001–0.0130
Vanua lava c.383 T > C	0	0	0	0	0	0	0	0	0	0	0
Coimbra c.592C > T	0	0	0	0	0	0	0	0	0	0	0
Mediterranean c.563C > T	0	0	0	0	0	0	0	0	0	0	0
Aures c.143 T > C	0	0	8	0	0	6	2	1	0	17 (6.75)	0.0423 0.0252– 0.0660
Quing Yan c.392G > T^a	ND	ND	ND	0	0	0	0	1	0	1 (0.40)	0.0023 0.0001–0.0130
Total	0	0	11	0	0	10	5	3	0	29 (11.51)

ISSN: 1475-2875