Table 2 Prevalence and molecular characteristics of G6PD deficiency in Lao PDR
| Â | This study | Hsia et al. 1993 (22) | Iwai et al. 2001 (20) | Kanchanavithayakul et al. 2017 (21) | Lover et al. 2018 (25) | Bancone et al. 2019 (23) | Ong et al. 2019 (24) |
|---|---|---|---|---|---|---|---|
G6PD enzyme deficient | |||||||
Male % | 5/78 (6.41%) | 15/74 (20.3%) | 21/291 (7.2%) | 31/141 (21.98%) | 30/910 3.30% | 106/1211 (8.8%) | ND |
Female % | 18/174 (10.34%) | ND | ND | 10/89 (11.24%) | ND | 79/1764 (4.50%) | ND |
Total % | 23/252 (9.13%) | 15/74 (20.27%) | 21/291 (7.2%) | 41/230 (17.8%) | 30/910 3.30% | 185/2978 (6.21%) | ND |
G6PD mutation | Â | Â | Â | Â | Â | Â | Â |
Gaohe 95A > G | ND | – | – | ND | ND | ND | ND |
Aures 143 T > C | 17 (6.75%) | ND | ND | ND | ND | ND | ND |
Asahi 202 G > A | ND | – | ND | ND | ND | ND | ND |
A 376 A > G | ND | – | ND | ND | ND | ND | ND |
Vanua Lava 383 T > C | – | ND | – | ND | ND | ND | ND |
Mahidol 487G > A | 2 (0.79%) | 2 (2.7%) | – | – | 1 (0.11%) | 4 (0.1%) | ND |
Chinese-3 493 A > G | ND | - | ND | ND | ND | ND | ND |
Mediterranean 563C > T | – | ND | ND | ND | – | ND | ND |
Coimbra 592C > T | – | ND | – | – | – | ND | ND |
Chinese-1 835 A > T | ND | – | ND | ND | ND | ND | ND |
Viangchan 871G > A with nt1311T | 1 (0.40) %) | 5 (6.8%) | 9 (3.1%) | 15 (6.5%) | 11 (1.21%) | 115 (3.9%) | 90 (4.4%) |
Jammu 871G > A with nt1311C | 2 (0.79%) | ND | ND | – | ND | ND | ND |
Chatham 1003 G > A | ND | – | – | ND | ND | ND | ND |
Chinese-5 1024 C > T | ND | ND | ND | – | ND | ND | ND |
Surabaya 1291G > A | ND | ND | – | ND | ND | ND | ND |
Union 1360C > T | 3 (1.19%) | 1 (1.4%) | – | 1 (0.4%) | 14 (1.54%) | 9 (0.3%) | ND |
Canton 1376G > T | 1 (0.4%) | – | – | 4 (1.7%) | 4 (0.44%) | 1 (0.03%) | ND |
Kaiping 1388G > A | 2 (0.79%) | 1 (1.4%) | – | 2 (0.9%) | ND | 4 (0.1%) | ND |
Quing Yan 392G > T | 1 (0.4%) | ND | ND | – | ND | 6 (0.2%) | ND |