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Table 3 Malaria in pregnancy treatment regimens and estimated costs

From: Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines

Anti-malarial drugs Strength/dosage form Median unit price (US $) Dosage/frequency Total number of tab/cap/vial/ampule Total cost (US$)
Oral medications
 Clindamycin 150 mg tab/cap 0.077 bmp 4 tabs given twice daily for 7 consecutive days 56 Tap-Cap 4.3
 Clindamycin 300 mg tab/cap 0.087 bmp 2 tabs given twice daily for 7 consecutive days 28 Tab-Cap 2.4
 Median clindamycin price      3.4
 Quinine 300 mg tab/cap 0.059 smp 2 tabs given twice daily for 7 consecutive days 28 Tab-Cap 1.65
 Clindamycin + Quinine      4.05*–5.95**
Parenteral medications
 Artesunate (IV) 60 mg/vial (3 vials for 51–75 kg individual) 1.91 smp 2.4 mg/kg at 0, 12, 24, and 48 h 12 Vial 22.92
 Quinine (IV) 250–300 mg/ml ampule 0.42 bmp 10 mg/kg at 0, 8, 16, and 24 h 12 ampules (including loading dose) 5.04
Artemisinin-based combinations
 Artemether + Lumefantrine (AL) 20 mg + 120 mg (SPC) 0.16 smp 4 tabs given at 0, 8, 24, 36, 48, and 60 h over 3 consecutive days 24 Tab-Cap 3.84
 Artesunate + Amodiaquine (AS–AQ) 100 mg + 270 mg (SPC) 0.85 smp 2 tabs given once daily for 3 consecutive days 6 Tab 5.1
 Dihydroartemisinin + Piperaquine (DHA–PPQ) 40 mg + 320 mg (SPC) 0.23 smp 4 tabs given once daily for 3 consecutive days 12 Tab-Cap 2.8
Medication for chemoprophylaxis in pregnancy
 Sulfadoxine + Pyrimethamine (SP) 500 mg + 25 mg (SPC) 0.039 smp 3 tabs given at every scheduled antenatal visit from 2nd trimester at least 1 month apart up to delivery 12 Tab-Cap§ 0.47
  1. bmp: Buyer median price; smp: Supplier median price; IV: intravenous
  2. Calculated from international medical products price guide30
  3. Single-pill combination
  4. § Calculated as a four antenatal care visit
  5. * Median price of Quinine + 300 mg Clindamycin combination
  6. ** Median price of Quinine + 150 mg Clindamycin combination
  7. In some instances, the quinine dose is reduced, and clindamycin dosage may vary
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