Table 3 Malaria in pregnancy treatment regimens and estimated costs
From: Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines
Anti-malarial drugs | Strength/dosage form | Median unit price†(US $) | Dosage/frequency | Total number of tab/cap/vial/ampule | Total cost (US$) |
|---|---|---|---|---|---|
Oral medications | |||||
 Clindamycin | 150 mg tab/cap | 0.077 bmp | 4 tabs given twice daily for 7 consecutive days | 56 Tap-Cap | 4.3 |
 Clindamycin | 300 mg tab/cap | 0.087 bmp | 2 tabs given twice daily for 7 consecutive days | 28 Tab-Cap | 2.4 |
 Median clindamycin price |  |  |  |  | 3.4 |
 Quinine | 300 mg tab/cap | 0.059 smp | 2 tabs given twice daily for 7 consecutive days | 28 Tab-Cap | 1.65 |
 Clindamycin + Quinine |  |  |  |  | 4.05*–5.95** |
Parenteral medications | |||||
 Artesunate (IV) | 60 mg/vial (3 vials for 51–75 kg individual) | 1.91 smp | 2.4 mg/kg at 0, 12, 24, and 48 h | 12 Vial | 22.92 |
 Quinine (IV) | 250–300 mg/ml ampule | 0.42 bmp | 10 mg/kg at 0, 8, 16, and 24 h | 12 ampules (including loading dose) | 5.04 |
Artemisinin-based combinations | |||||
 Artemether + Lumefantrine (AL) | 20 mg + 120 mg (SPC)‡ | 0.16 smp | 4 tabs given at 0, 8, 24, 36, 48, and 60 h over 3 consecutive days | 24 Tab-Cap | 3.84 |
 Artesunate + Amodiaquine (AS–AQ) | 100 mg + 270 mg (SPC)‡ | 0.85 smp | 2 tabs given once daily for 3 consecutive days | 6 Tab | 5.1 |
 Dihydroartemisinin + Piperaquine (DHA–PPQ) | 40 mg + 320 mg (SPC)‡ | 0.23 smp | 4 tabs given once daily for 3 consecutive days | 12 Tab-Cap | 2.8 |
Medication for chemoprophylaxis in pregnancy | |||||
 Sulfadoxine + Pyrimethamine (SP) | 500 mg + 25 mg (SPC)‡ | 0.039 smp | 3 tabs given at every scheduled antenatal visit from 2nd trimester at least 1 month apart up to delivery | 12 Tab-Cap§ | 0.47 |