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Fig. 1 | Malaria Journal

Fig. 1

From: RDL mutations in Guangxi Anopheles sinensis populations along the China–Vietnam border: distribution frequency and evolutionary origin of A296S resistance allele

Fig. 1

Diagnostic PCR-RFLP tests to detect the T345S mutation. The 167 bp amplicon is undigested by HpyCH4 III for homozygous TCG (mutant 345SS), and cut into two fragments of 83 bp and 84 bp for homozygous ACG (wild 345TT) that co-migrate in the agarose gel and cannot be distinguished. A combined pattern (two bands 167 bp + 83/84 bp) is displayed for heterozygotes

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