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Table 5 Associations between RBC variants and temperature adjusted for parasite density (anti-disease immunity) in parasitaemic children

From: Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study

Red cell variantsVariantUnadjustedAdjusted*
Change in temperature in  °C (95% CI)p-valueChange in temperature in  °C (95% CI)p-value
Haemoglobin variantAAReferenceReference
AS− 0.13 (− 0.22, − 0.04)0.003− 0.13 (− 0.21, − 0.05)0.002
SS0.09 (− 0.68, 0.86)0.820.22 (− 0.52, 0.96)0.56
Alpha thalassaemia variantNormalReferenceReference
α−/αα− 0.10 (− 0.17, − 0.03)0.003− 0.09 (− 0.21, 0.02)0.11
α−/−α− 0.08 (− 0.24, 0.08)0.31− 0.16 (− 0.41, 0.08)0.20
G6PD genotypeNormal (male)ReferenceReference
Hemizygotes− 0.12 (− 0.25, 0.01)0.07− 0.19 (− 0.31, − 0.06)0.003
Normal (female)ReferenceReference
Heterozygotes− 0.12 (− 0.24, 0.01)0.07− 0.09 (− 0.21, 0.02)0.11
Homozygotes− 0.08 (− 0.37, 0.20)0.57− 0.16 (− 0.41, 0.08)0.20
  1. * Adjusted for parasite density, age, average household EIR, and study site