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Table 5 Associations between RBC variants and temperature adjusted for parasite density (anti-disease immunity) in parasitaemic children

From: Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study

Red cell variants

Variant

Unadjusted

Adjusted*

Change in temperature in  °C (95% CI)

p-value

Change in temperature in  °C (95% CI)

p-value

Haemoglobin variant

AA

Reference

Reference

AS

− 0.13 (− 0.22, − 0.04)

0.003

− 0.13 (− 0.21, − 0.05)

0.002

SS

0.09 (− 0.68, 0.86)

0.82

0.22 (− 0.52, 0.96)

0.56

Alpha thalassaemia variant

Normal

Reference

Reference

α−/αα

− 0.10 (− 0.17, − 0.03)

0.003

− 0.09 (− 0.21, 0.02)

0.11

α−/−α

− 0.08 (− 0.24, 0.08)

0.31

− 0.16 (− 0.41, 0.08)

0.20

G6PD genotype

Normal (male)

Reference

Reference

Hemizygotes

− 0.12 (− 0.25, 0.01)

0.07

− 0.19 (− 0.31, − 0.06)

0.003

Normal (female)

Reference

Reference

Heterozygotes

− 0.12 (− 0.24, 0.01)

0.07

− 0.09 (− 0.21, 0.02)

0.11

Homozygotes

− 0.08 (− 0.37, 0.20)

0.57

− 0.16 (− 0.41, 0.08)

0.20

  1. * Adjusted for parasite density, age, average household EIR, and study site