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Fig. 3 | Malaria Journal

Fig. 3

From: Moringa oleifera treatment increases Tbet expression in CD4+ T cells and remediates immune defects of malnutrition in Plasmodium chabaudi-infected mice

Fig. 3

Long-term treatment with Moringa pellets increase the number of activated effector and TNF secretion in post infection treated mice. C57BL/6 mice were fed Moringa pellets for 3 weeks pre-infection or post-infection; control mice were fed control pellets. Mice were infected with a 1 × 105P. chabaudi AS. Mice were sacrificed 6 weeks later at day 23 post infection. a Number of activated effector CD4+ T cells identified using CD4+CD44hiCD62Llo and analysed by flow cytometry. Percentage of CD4+ T cells producing b IFNγ and c TNF, respectively. Data represent 3 mice per group from a representative experiment of 2 independent experiments. Error bars represent SEM and significance was determined by One-Way ANOVA followed by comparisons between individual groups. *p < 0.05. Pre Moringa treatment before infection, Post Moringa treatment after infection, Control No Moringa treatment but infected, Uninf Moringa treatment but not infected control, L.O.D limit of detection

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